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Nucleic acid–based antiviral therapeutics that have entered clinical trials

Journal: Nature Biotechnology

Article Title: RNA interference against viruses: strike and counterstrike

doi: 10.1038/nbt1369

Figure Lengend Snippet: Nucleic acid–based antiviral therapeutics that have entered clinical trials

Article Snippet: HCV , Ribozyme (Heptazyme) a , IRES , Phase 2 studies discontinued , Ribozyme Pharmaceuticals (Boulder, CO, USA; renamed Sirna, now part of Merck) , .

Techniques: Dominant Negative Mutation, shRNA, Plasmid Preparation, Small Interfering RNA